11C-Methionine Positron Emission Tomography (PET) for Target Definition of Recurrent Glioblastoma Multiforme in the Reirradiation Planning

The effect of fasting on Positron Emission Tomography (PET) imaging

As a nuclear approach, Positron Emission Tomography (PET) is a functional imaging technique which is based on the detection of gamma ray pairs emitted by a positron-emitting radionuclide. There are certain limitations to this technique such as normal tissue uptake. Therefore, it has been recommended that patients prepare before scanning. Fasting for a short while before PET imaging is an exampl...

Positron Emission Tomography ( PET )

The principle of image formation in tomography is summarised. The principle ofpositron electron annihilation is introduced. The principle of coincidence techniques is illustrated. Detector development and perspectives for positron emission tomography (PET) instrumentation for medical research is presented. The physical processes in in positron annihilation, photon scattering and tomograph desig...

Extracranial metastasis of multiforme glioblastoma detected by 11C-methionine brain PET/CT.

[11C]-Methionine Positron Emission Tomography in the Postoperative Imaging and Followup of Patients with Primary and Recurrent Gliomas

We investigated the sensitivity and specificity of [(11)C]-methionine positron emission tomography ([(11)C]-MET PET) in the management of glioma patients. We retrospectively analysed data from 53 patients with primary gliomas (16 low grade astrocytomas, 15 anaplastic astrocytomas and 22 glioblastomas) and Karnofsky Performance Status (KPS) > 70. Patients underwent [(11)C]-MET PET scans (N = 249...

L-(methyl-11C) methionine positron emission tomography for target delineation in resected high-grade gliomas before radiotherapy.

PURPOSE Using magnetic resonance imaging (MRI), residual tumor cannot be differentiated from nonspecific postoperative changes in operated patients with brain gliomas. The higher specificity and sensitivity of L-(methyl-11C)-labeled methionine positron emissions tomography (MET-PET) in gliomas has been demonstrated in previous studies and is the rationale for the integration of this investigati...